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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14348 | Auristatin E | Microtubule Associated | |
Auristatin E, a cytotoxic tubulin modifier, disrupts cell division by inhibiting tubulin polymerisation. This compound demonstrates potent and selective antitumor activities, serving as an MMAE analog and cytotoxin in an... | |||
T6897 | Monomethyl auristatin E | Vedotin,MMAE | Apoptosis , Microtubule Associated |
Monomethyl auristatin E (MMAE) (MMAE), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin and also has inhibition of antibody-drug conjugates (ADCs) activity. | |||
T18319 | MC-Val-Cit-PAB-Auristatin E | Others | |
MC-Val-Cit-PAB-Auristatin E is an antibody-drug conjugate (ADC) linker compound featuring Auristatin E, a potent cytotoxic tubulin modifier, connected through the MC-Val-Cit-PAB linker, exhibiting significant antitumor a... | |||
T74483 | Aminobenzenesulfonic auristatin E | ||
Aminobenzenesulfonic auristatin E is a potent antitumor agent-linker conjugate for Antibody-Drug Conjugates (ADC). It utilizes Auristatin E (a cytotoxic tubulin modifier) connected through the ADC linker, Aminobenzenesul... | |||
T74484 | Aminobenzenesulfonic auristatin E TFA | ||
Aminobenzenesulfonic Auristatin E TFA, an agent-linker conjugate for ADC, exhibits potent antitumor activity. It employs Auristatin E (a cytotoxic tubulin modifier) connected through the ADC linker Aminobenzenesulfonic [... | |||
T10948 | MMAE-d8 | D8-MMAE,D8-Monomethyl auristatin E | Others |
D8-MMAE (D8-Monomethyl auristatin E) is an effective mitotic inhibitor and tubulin inhibitor, deuterated MMAE. | |||
T18312 | Mc-MMAE | Maleimidocaproyl-monomethylauristatin E | Microtubule Associated |
Mc-MMAE (Maleimidocaproyl-monomethylauristatin E) is a drug-linker conjugate for ADC. Mc-MMAE is a maleimidocaproyl-conjugated monomethyl auristatin E, which is a potent tubulin inhibitor. | |||
T70958 | Dov-Val-Dil-OH TFA | ||
Dov-Val-Dil-OH is a useful chemical intermediate for synthesis of auristatin-related compounds, such as Monomethyl auristatin E (MMAE), Auristatins are antimitotic agents which inhibits cell division by blocking the po... | |||
T18473 | N3-PEG3-vc-PAB-MMAE | Others | |
N3-PEG3-vc-PAB-MMAE, a drug-linker conjugate designed for Antibody-Drug Conjugates (ADC), features the integration of monomethyl auristatin E (MMAE), a tubulin inhibitor, via a 3-unit polyethylene glycol (PEG) linker. Th... | |||
T79039 | GGGDTDTC-Mc-vc-PAB-MMAE | ||
GGGDTDTC-Mc-vc-PAB-MMAE is a drug-linker conjugate for antibody-drug conjugates (ADCs), incorporating the tubulin inhibitor monomethyl auristatin E (MMAE) as the cytotoxic component [1]. | |||
T40568 | Fmoc-MMAE | ||
Fmoc-MMAE, a protective group-conjugated variant of monomethyl auristatin E (MMAE), serves as a powerful inhibitor of tubulin. It finds application in the synthesis of antibody-drug conjugates (ADC). | |||
T18736 | SuO-Val-Cit-PAB-MMAE | Others | |
SuO-Val-Cit-PAB-MMAE is an ADC (antibody-drug conjugate) linker comprising the anti-mitotic monomethyl auristatin E (MMAE, a tubulin inhibitor) connected through the SuO-Val-Cit-PAB peptide. | |||
T18679 | SC-VC-PAB-MMAE | Others | |
SC-VC-PAB-MMAE is a potent antitumor drug-linker conjugate for antibody-drug conjugates (ADCs), comprising the anti-mitotic agent monomethyl auristatin E (MMAE, a tubulin inhibitor) connected through the cleavable linker... | |||
T17817 | DBCO-(PEG)3-VC-PAB-MMAE | Others | |
DBCO-(PEG)3-VC-PAB-MMAE is a chemical compound where monomethyl auristatin E (MMAE), a potent tubulin inhibitor acting as a toxin payload in antibody-drug conjugates, is conjugated to a DBCO-(PEG)3-vc-PAB linker. | |||
T18303 | Mal-Phe-C4-VC-PAB-MMAE | Others | |
Mal-Phe-C4-VC-PAB-MMAE is a chemical compound resulting from the conjugation of monomethyl auristatin E (MMAE), a potent tubulin inhibitor serving as a toxin payload in antibody-drug conjugates, with a Mal-Phe-C4-VC-PAB ... | |||
T39307 | Azido-PEG4-Val-Cit-PAB-MMAE | Azido-PEG4-Val-Cit-PAB-MMAE | |
Azido-PEG4-Val-Cit-PAB-MMAE is a drug-linker conjugate for antibody-drug conjugates (ADCs), comprising the anti-mitotic agent monomethyl auristatin E (MMAE, a tubulin inhibitor), connected through the cleavable linker Az... | |||
T82380 | Fmoc-VAP-MMAE | ||
Fmoc-VAP-MMAE is a conjugate utilized in antibody-drug conjugates (ADCs), comprising a tubulin inhibitor, monomethyl auristatin E (MMAE), connected via an ADC linker, and shielded by a fluorenylmethyloxycarbonyl (Fmoc) p... | |||
T17789 | DBCO-(PEG2-VC-PAB-MMAE)2 | Others | |
DBCO-(PEG2-VC-PAB-MMAE)2 consists of Monomethyl auristatin E (MMAE), a toxin payload in antibody-drug conjugate [1], conjugated to the cleavable linker DBCO-(PEG2-VC-PAB)2. MMAE, a potent tubulin inhibitor, serves as the... | |||
T77838 | Telisotuzumab vedotin | ABBV-399 | |
Telisotuzumab vedotin (ABBV-399), an antibody-drug conjugate (ADCs), targets c-Met and comprises the cytotoxic agent Monomethyl Auristatin E (MMAE), the Telisotuzumab antibody, and a cleavable mc-val-cit-PABC linker. Thi... | |||
T77883 | Val-Ala-PAB-MMAE | ||
Val-Ala-PAB-MMAE is a drug-linker conjugate utilized in antibody-drug conjugates (ADCs), composed of the ADC linker Val-Ala-PAB and the cytotoxic agent monomethyl auristatin E (MMAE), which serves as a potent inhibitor o... |